在色氨酸存在下利用多壁碳纳米管糊电极和萘酚介质构成的伏安传感器测定N-乙酰半胱氨酸(英文)

编号：NMJS05098

篇名：在色氨酸存在下利用多壁碳纳米管糊电极和萘酚介质构成的伏安传感器测定N-乙酰半胱氨酸(英文)

作者：Mohsen Keyvanfard； Maryam Tahmasbi； Hassan Karimi-Maleh； Kha

关键词：N‐actylcysteine Tryptophan Multiwall carbon nanotube Naphthol green； Sensor；

机构： Department of chemistry,Majlesi Branch,Islamic Azad University； Department of chemistry,Shahreza Bra

摘要： A multiwall carbon nanotube modified electrode prepared by incorporating multiwall carbon nanotubes in the electrode of a sensor and naphthol green as a homogeneous mediator was used as a voltammetric sensor for the determination of N‐actylcysteine(N‐AC) in the presence of trypto-phan(Trp). The voltammograms of differential pulse voltammetry of N‐AC in a mixture with Trp were separated from each other by a potential difference of 200 mV, which allowed the determina-tion of both N‐AC and Trp simultaneously. Under the optimum conditions, the electrocatalytic cur-rents increased linearly with N‐AC concentration in the range of 0.25–400 μmol/L(two linear seg-ments with different slopes). The detection limit for N‐AC was 0.08 μmol/L. The kinetic parameters of the system were determined using electrochemical methods. The method was applied for the determination of N‐AC in drug and urine samples.